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New Publication in Sci Rep

http://www.nature.com/articles/srep14703

My experience at Fly Lab by Anna Shiney

實驗室發表的PRL於發育過程的表現模式被選為BMC Developmental Biology 2013年5月份的 Image highlight!

     One of the leading causes of cancer-related death is cancer metastasis. However, the understanding the genetic basis of the metastatic process is very limited. In recent years, Phosphatase of regenerating liver (PRL) family, a subgroup of protein tyrosine phosphatase superfamily including PRL-1, PRL-2, and PRL-3, has been implicated in a variety of metastatic cancers and emerged as therapeutic targets. However, the understanding of the molecular function and substrates of PRL phosphatases is limited. In addition, the developmental roles of the evolutionary highly conserved PRL phosphatases have not yet been addressed. One of our interests is to examine the role or PRL in development by using Drosophila, Sea urchin and zebrafish as model organisms. As a pioneer study of PRL function during development, we believe that our studies will makes a contribution to the understanding of the metastatic role of human PRL phosphatases.

狂賀!! 實驗室王冠捷同學通過大專生參與國科會研究計畫補助

                 

FLY Lab

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